CRESTOR? contains rosuvastatin, a potent HMG-CoA reductase inhibitor (statin) used in the management of hypercholesterolemia and mixed dyslipidemia. It works by reducing cholesterol synthesis in the liver, leading to a significant decrease in low-density lipoprotein (LDL) cholesterol and triglycerides, while moderately increasing high-density lipoprotein (HDL) cholesterol. CRESTOR? is widely used to reduce the risk of cardiovascular events such as heart attack and stroke in high-risk patients.